Deep Dive into Research on Amaranth & Squalene

Deep Dive into Research on Amaranth & Squalene

In the quest for optimal health and well-being, we often overlook the incredible potential of nature's treasures. That all changed when we learned about Amaranth, an ancient grain that has captured the attention of academic researchers and health enthusiasts alike. Here, we briefly summarize some of the research around Amaranth and Squalene so that you can determine how best to add it to your wellness plan.

 

A detailed and comprehensive study of amaranth (Amaranthus cruentus L.) oil fatty profile (Manuel León-Camacho · Diego L. García-González Ramón Aparicio)

In this article published in 2014 in the European Food Research and Technology journal, León-Camacho and Aparicio have carefully studied the major and minor components present in Amaranth oil, including fatty acids, triglycerides, sterols, methylsterols, terpenic and aliphatic alcohols, tocopherols, and hydrocarbons. Sophisticated techniques like mass spectrometry, HRGC, and HPLC have helped identify and quantify these compounds, comparing them to those found in other edible oils. Notably, Amaranth oil contains a significant amount of Squalene, known for its many beneficial properties. It also boasts high levels of n-alkenes, which contribute to its unique characteristics. Excitingly, the findings suggest potential applications of Amaranth oil in the pharmaceutical industry.

 

Biological Importance and Applications of Squalene and Squalane (Se-Kwon Kim*,†,1 and Fatih Karadeniz*)

Published in the 2012 edition of Advances in Food & Nutrition Research, Kim & Karadeniz investigate Squalene, a polyunsaturated hydrocarbon that exists in abundance in certain fish oils, notably shark liver oil, as well as in smaller quantities in some vegetable oils. Interestingly, Squalene constitutes 13% of human sebum, playing a significant role in our bodies. The ancient use of shark liver oil in traditional medicine sparked interest in Squalene, leading to extensive research. Excitingly, numerous studies have highlighted the diverse bioactivities of Squalene. These compounds have shown potential as anticancer agents, antioxidants, drug carriers, detoxifiers, and even as agents for skin hydration and nourishment. Animal models and laboratory experiments have yielded promising results, positioning Squalene as crucial substances with vast practical and clinical applications. 

 

Squalene: A natural triterpene for use in disease management and therapy (L. Harivardhan Reddy ⁎, Patrick Couvreur)

In this study, Reddy & Couvreur show that Squalene has significant dietary benefits, biocompatibility, and inertness, making it widely used as an excipient in pharmaceutical formulations for disease management and therapy. The study also revealed that squalene acts as a protective agent, effectively reducing chemotherapy-induced side effects. Furthermore, Squalene demonstrated chemopreventive activity and played a role in enhancing the immune response to associated antigens, indicating its potential for vaccine delivery applications. With its excellent oral absorption, Squalene was found to improve the oral delivery of therapeutic molecules. These valuable findings from the study position Squalene as an intriguing candidate for pharmaceutical applications, particularly in the delivery of vaccines, drugs, genes, and other biological substances.

 

Squalene And Its Potential Clinical Uses (Gregory S. Kelly, N.D.)

In this article, Kelly shows that when we consume squalene through our diet, about 60 percent of it is absorbed. It circulates in our bloodstream with very low density lipoproteins and can be found throughout our tissues, with the highest concentration in our skin where it forms a major part of the surface lipids. Interestingly, Squalene acts as a protector for our skin, shielding it from damage caused by UV rays and other sources of radiation. When Squalene is given to mice, it has shown to enhance cellular and immune functions. Additionally, Squalene can attract and trap certain harmful substances in the body. This characteristic makes it potentially useful in reducing cholesterol and triglyceride levels in animals, and it may also enhance the effects of certain cholesterol-lowering medications in humans. Currently, Squalene is being explored as an adjunctive therapy for various types of cancers, although human trials are needed to validate its potential in cancer treatment. The study highlights the importance of squalene and its potential therapeutic applications, paving the way for future research and investigations into its clinical uses.

 

The research on Amaranth and Squalene has unveiled fascinating insights into the potential health benefits of these natural compounds. Amaranth oil, with its rich composition of fatty acids, triglycerides, and unique chemical compounds like Squalene, shows promise benefits for various applications, ranging from skincare to cancer therapy. Incorporating Amaranth oil into your daily routine can provide you with essential nutrients, antioxidant protection, and potential support for your overall well-being.


Wellamar offers a full range of Amaranth-based products high in Squalene.
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